Crypto custodian BitGo Prime will offer OTC access to prediction markets via a partnership with Susquehanna Crypto, the digital asset-focused unit of the global quantitative trading firm.

Traders will be able to post stablecoin and other crypto as collateral, meaning they won't have to liquidate their digital asset positions to participate in the burgeoning predictions space. The service will be offered through BitGo's trading interface and tap Susquehanna Crypto's bilateral execution capabilities and liquidity, according to an announcement on Tuesday. 

"Prediction markets have matured into a genuine institutional asset class," said Chase Lax, CEO at Susquehanna Crypto. "We've long believed in their power as a tool for price discovery around real-world events. Partnering with BitGo to give institutional clients access to these markets is a natural extension of the work we've been doing in this space."

BitGo's service is aimed at institutional participants like hedge funds, family offices, and ultra-high-net-worth individuals that may find retail-focused trading platforms insufficient. The announcement argues that institutional adoption of prediction markets "has remained constrained by the lack of integrated infrastructure for custody, collateral management, and OTC execution."

The offering will allow clients to post U.S. dollar, stablecoins, bitcoin and other crypto as collateral to trade any listed contract for $100,000 or greater, according to BitGo Global Head of Trading Matt Ballensweig in the release.

Prediction markets allow users to wager on the outcome of a wide range of future events, though the most liquid markets today are typically tied to politics, sports or entertainment.

Trading volumes on the two largest prediction markets, Polymarket and Kalshi, have grown consistently month after month since mid-2025. Kalshi and Polymarket have also both struck deals with major sports, media, and entertainment franchises in a bid to grow their user bases. 

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While the Commodity Futures Trading Commission has claimed exclusive jurisdiction over event contracts under to Commodity Exchange Act — with CFTC executives even filing a brief in support of the sector in February — several states allege platforms like Kalshi fall afoul of local gaming and gambling laws. 

Market makers, including Susquehanna, are an increasingly important part of the prediction market ecosystem. These companies post continuous two-way quotes on the binary "Yes/No" event contracts, enabling traders to enter or exit positions without waiting for a counterparty, as well as reducing slippage. 

Susquehanna was named the first official designated market maker on Kalshi in 2024.

BitGo went public via a traditional IPO on Jan. 22, raising $212.8 million at an over $2 billion valuation.